Clinical Research: The Best of Both Worlds – LC/Q-TOF as a Method to Detect a Targeted List of 35 Drugs and Metabolites in Urine with Retrospective Data Mining Capabilities


Compliance testing continues to be an essential component of the drug testing market. As an alternative to conventional immunoassay screens with reflex to confirmation, we developed a dual identification strategy for drug screening and confirmation with one injection for clinical research purposes. Making use of the quadrupole-time-of-flight mass spectrometer’s (Q-TOF) quadrupole, we combined fragmentation pattern with accurate mass, retention time, and isotope fidelity to identify analytes of interest with increased accuracy

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