Separation of Enantiomers of Amphetamine-Related Drugs and Their Structural Isomers


This Application Note demonstrates the separation of enantiomers of amphetamine-related
drugs and their positional isomers as well as enantiomers of the
same compounds. This separation was performed using chiral phase columns with
the Agilent 1260 Infinity II SFC System. The qualitative detection and quantitative
determination of both the structural isomers and enantiomers was achieved using
the Agilent 6495 triple quadrupole MS and the Agilent 6150 single quadrupole
MSD.

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