Feed Speed and Overfeed Volume – New Parameters for Injection in SFC

New Parameters for Injection in Supercritical Fluid
Chromatography
This Technical Overview demonstrates and discusses the influence of the injection
parameters Feed Speed and Overfeed Volume on chromatographic separation.
These parameters were introduced with the Agilent 1260 Infinity II Supercritical
Fluid Chromatography (SFC) Multisampler. The influence on the isocratic
separation of closely eluting compounds, shown for different injection volumes
commonly used in analytical SFC, and guidelines for optimization are given.

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