Optimizing performance of Agilent ELSD


This Technical Overview demonstrates how to achieve highest performance of the
Agilent 1290 Infinity Evaporative Light Scattering Detector (ELSD). This Technical
Overview shows and explains the influence of different parameter settings on
sensitivity and resolution.
The primary advantage of the Agilent 1290 Infinity ELSD is the ability to
adjust settings such as evaporator temperature and gas flow to remove, for
example, dimethylsulfoxide (DMSO) at the low evaporator temperature of 30 °C.
Additionally, this Technical Overview summarizes the influence of evaporator
temperature and gas flow on the limit of detection (LOD). With the presented tips,
it is easy to get the best ELSD results regarding sensitivity and resolution without
further tedious method modification.

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